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Synovate 0.05% Ointment 10gm

Generic: Clobetasol Propionate

Type: Cream

Pack Size: 10gm

Clobetasol Propionate 0.05% Clobetasol is a steroid, used in the treatment of allergic skin conditions.


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Discount Price: ৳ 43.2
MRP: ৳ 45 4% Off

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✅ Description:

Synovate 0.05% Ointment contains Clobetasol Propionate, which belongs to the group of medicines called Topical corticosteroids. It is used to manage inflammatory skin conditions such as psoriasis, eczema, and dermatitis that have not responded to milder steroid creams or ointments.

Psoriasis

Psoriasis is a chronic skin condition characterized by red, flaky, crusty patches covered with silvery scales. The severity of psoriasis varies widely among individuals. For some, it is a minor irritation, while for others, it significantly affects their quality of life. Psoriasis involves cycles of mild or no symptoms followed by periods of more severe symptoms.

Eczema

Eczema refers to a group of conditions that cause the skin to become dry and irritated.

Lichen Planus

Lichen planus is a rash that can appear on various parts of the body, including the inside of the mouth. On the skin, it can be very itchy, though not always.

Lupus

Lupus is a long-term condition that causes joint pain, skin rashes, and fatigue. While there is no cure, early treatment can help improve symptoms.

Synovate 0.05% Ointment is not recommended for use in patients with other bacterial, fungal, or viral infections (such as herpes simplex, chicken pox, and tuberculosis). Before using Synovate 0.05% Ointment, inform your doctor if you have a skin infection, diabetes, adrenal gland problem, scheduled surgery, acne, plaques around your mouth, underarms, anus, or genitals, and liver diseases.

Safety Advices


Alcohol
UNSAFE

Synovate 0.05% Ointment may not interact with alcohol.


Pregnancy
CONSULT YOUR DOCTOR

Synovate 0.05% Ointment should be used during pregnancy only if recommended by your doctor. Consult your doctor before using Synovate 0.05% Ointment.


Breastfeeding
CONSULT YOUR DOCTOR

Synovate 0.05% Ointment should be used with caution by breastfeeding women. Consult your doctor before using Synovate 0.05% Ointment.


Driving
SAFE

Synovate 0.05% Ointment is not expected to have any effects on your ability to drive and use machines.


Kidney
CONSULT YOUR DOCTOR

Synovate 0.05% Ointment should be used with caution in patients with kidney disease. Consult your doctor before using Synovate 0.05% Ointment


Liver
CONSULT YOUR DOCTOR

Synovate 0.05% Ointment should be used with caution in patients with liver disease. Consult your doctor before using Synovate 0.05% Ointment.

Similar Products

✔️ Uses of Synovate 0.05% Ointment

Autoimmune skin diseases such as psoriasis, eczema, lichen planus, and discoid lupus erythematosus

✔️ How does Synovate 0.05% Ointment work?

It works by blocking the production of certain chemical messengers that make the skin red, swollen and itchy.

✔️ Side Effects of Synovate 0.05% Ointment

Prolonged use or treatment of extensive areas can lead to systemic absorption and hypercorticism. Intensive treatment can cause skin atrophy, thinning, striae, and superficial blood vessel dilation, especially with occlusive dressings or skin folds. Rarely, it can provoke pustular psoriasis. Reports include pigmentation changes and hypertrichosis. If hypersensitivity appears, discontinue use immediately. Symptom exacerbation may occur.

✔️ Quick Suggestions:
  • Clobetasol is used to treat redness, swelling, itching, and discomfort of various skin conditions.
  • It should be applied to the affected areas as a thin film, two times daily, or as advised by your doctor.
  • Do not use it more often or for longer than advised by your doctor.
  • Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • If you think the area of skin you are treating has become infected you should stop using Clobetasol and consult your doctor.
  • Consult your doctor if your skin condition has not improved after four weeks of treatment. Do not use it for more than 4 consecutive weeks at a time.
✔️ Synovate is indicated for adults, the elderly, and children over 1 year for the following dermatoses:
  • Psoriasis (excluding widespread plaque psoriasis)
  • Recalcitrant dermatoses
  • Lichen planus
  • Discoid lupus erythematosus
  • Other skin conditions unresponsive to less potent steroids
✔️ Pharmacology

Clobetasol Propionate is a highly potent topical corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. It inhibits late-phase allergic reactions through various mechanisms, such as reducing mast cell density, chemotaxis, and eosinophil activation, decreasing cytokine production, and inhibiting arachidonic acid metabolism.

✔️ Dosage & Administration of Synovate 0.05% Ointment

For adults, the elderly, and children over 1 year, apply a thin layer to the affected areas twice daily, rubbing in gently and completely. For resistant lesions, especially with hyperkeratosis, occlusion with polythene film overnight may enhance the effect. Limit treatment to 2 consecutive weeks with a maximum of 50 gm per week. In children, limit courses to five days and review weekly.

Use creams for moist or weeping surfaces and ointments for dry, lichenified, or scaly lesions.

✔️ Interaction

Co-administered drugs that inhibit CYP3A4 (e.g., ritonavir, itraconazole) can inhibit corticosteroid metabolism, increasing systemic exposure.

✔️ Contraindications
  • Rosacea, acne vulgaris, and perioral dermatitis
  • Primary cutaneous viral infections (e.g., herpes simplex, chickenpox)
  • Hypersensitivity to the preparation
  • Primary infected skin lesions caused by fungi (e.g., candidiasis, tinea) or bacteria (e.g., impetigo)
  • Perianal and genital pruritus
  • Dermatoses in children under 1 year, including dermatitis and napkin eruptions
✔️ Pregnancy & Lactation

Limited data exists on Clobetasol Propionate use in pregnant women. Topical corticosteroids in pregnant animals can cause fetal development abnormalities. Use during pregnancy and lactation should only be if the benefits outweigh the risks. Unknown if excreted in human milk, caution is advised for nursing women.

✔️ Precautions & Warnings

Avoid long-term continuous therapy, especially in infants and children, due to the risk of adrenal suppression. Limit facial treatments and occlusion, as the face is prone to atrophic changes. Avoid eye contact to prevent glaucoma or cataract. Topical corticosteroids can be hazardous in psoriasis. Use antimicrobial therapy for infected inflammatory lesions. Withdraw corticosteroids if infection spreads and use systemic antimicrobials.

✔️ Storage Conditions:

Store below 30°C, protected from light and moisture. Do not freeze. Keep out of reach of children.

Frequently Asked Questions (FAQ)

Acute overdose is unlikely, but chronic overuse or misuse can cause hypercortisolism, necessitating discontinuation of topical steroids.

Local skin reactions are rare with Clobetasol. It is used to treat skin diseases, reactions, and eczemas. However, skin reactions can occur in hypersensitive individuals. It is important to leave the treated area open, as occlusive dressings can lead to skin reactions. Sometimes, reactions are caused by excipients in the medication. Inform your doctor immediately if you encounter any skin reactions.

No, do not stop taking Clobetasol before completing the full course of treatment, even if you feel better. Stopping Clobetasol early can cause your symptoms to return. Always finish the prescribed treatment duration.

Clobetasol is not recommended for children under 1 year of age. Its use should also be avoided in older children and adolescents due to a higher risk of side effects, including immune system suppression and atrophic changes. In rare cases, a doctor may recommend it, but treatment is usually limited to 5 days with weekly reviews.

No, Clobetasol should not be used on the face, armpits, groin, or areas with atrophy unless specifically prescribed by a doctor. If prescribed, limit facial application to a maximum of 5 days. Always consult your physician before using Clobetasol on sensitive areas.

No, Clobetasol should not be used for a long time. It is generally prescribed for 2 consecutive weeks only. However, the treatment can be extended for chronic inflammatory conditions. Consult your physician before using this medication for an extended period.

Severe skin reactions are quite rare with Clobetasol. It is an anti-inflammatory drug used to treat skin diseases, reactions, and eczema. However, hypersensitive individuals may experience skin reactions. It is important to leave the affected area open after applying Clobetasol, as occlusive dressings can lead to skin reactions. The medication itself may not cause a reaction, but excipients can sometimes cause issues. Inform your doctor immediately if you experience any skin reactions.

No, Clobetasol is not an antimicrobial or antifungal agent. It is a steroid medication that can suppress the immune system and increase the risk of infections. Do not use Clobetasol to treat infections. If inflammatory lesions become infected or if there is any spread of infection, consult your doctor immediately for appropriate antimicrobial therapy.
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Check our pricing section for Synovate 0.05% Ointment 10gm price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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